Clinical Case Scenario
A 48-year-old man presents with cough and fever, and a nasopharyngeal swab confirms influenza A. He begins treatment with oseltamivir but returns to the ED within 24 hours with high-grade fever, multifocal lung opacities on chest x-ray, and respiratory failure necessitating intubation and ICU admission. Blood cultures and bronchoalveolar lavage (BAL) reveal methicillin-resistant Staphylococcus aureus (MRSA). After receiving a 2-liter crystalloid bolus and appropriate antibiotics, he develops progressive hypotension. A central venous catheter (CVC) is inserted via the right internal jugular vein. His vital signs show mean arterial pressure (MAP) at 45 mm Hg, central venous pressure (CVP) at 11 mm Hg, central venous oxygen saturation (ScVO2) at 89%, arterial lactate at 10.2 mmol/L, and urine output of 10 cc/hr over the last 4 hours.
Which of the following statements is correct about the next step in management?
