Clinical Case Scenario
A 35-year-old male patient with severe hepatic encephalopathy due to liver failure presents with confusion, lethargy, and asterixis. Laboratory tests show significantly elevated ammonia levels (210 µmol/L) and impaired kidney functions (urea 55 mmol/L and creatinine 210 µmol/L). Lactate and bicarbonate levels in blood gas are at 10 mmol/L and 14 mmol/L respectively. Despite maximal medical therapy, including lactulose and rifaximin, the patient's condition worsens. Continuous Renal Replacement Therapy (CRRT) is initiated.
What is the primary rationale for using CRRT in this patient, and what key technical considerations should be noted?
