Clinical Case Scenario
A 65-year-old male patient with a history of chronic kidney disease and hypertension was admitted to the ICU with severe metabolic acidosis. Despite standard medical therapy, his peripheral venous blood gas analysis shows pH: 7.23, base excess [BE]: -4 mEq/L, PaCO2: 32 mm Hg, and lactate: 6 mmol/L. The medical team decided to administer sodium bicarbonate to correct the acidosis.
What is one of the main potential risks associated with the use of sodium bicarbonate therapy in ICU patients with severe metabolic acidosis and AKI?
