Clinical Case Scenario

A patient in the intensive care unit with septic shock and acute kidney injury is receiving continuous Veno-venous hemofiltration (CVVH). Over the past few hours, the treating team has become concerned about rising filter pressures and possible early filter clotting. The CRRT machine displays the following pressures:

  • Filter pressure: 180 mmHg
  • Return pressure: 90 mmHg
  • Effluent pressure: 20 mmHg

What is the transmembrane pressure?