MCQs – Tropical Acute Kidney Injury (AKI) – Nephro Critical Care Society

MCQs – Tropical Acute Kidney Injury (AKI)

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1. Which of the following best distinguishes Tropical AKI from Sepsis-associated AKI (SA-AKI)?

A. Tropical AKI occurs only in ICU settings

B. Tropical AKI has diverse etiologies including infections, toxins, and envenomation

C. SA-AKI has heterogeneous causes compared to Tropical AKI

D. SA-AKI rarely involves systemic inflammation

2. Which of the following mechanisms is commonly associated with AKI in severe malaria?

A. Immune-mediated glomerulonephritis

B. Cytoadherence of parasitized erythrocytes causing microvascular obstruction

C. Renal artery thrombosis

D. Pure pre-renal hypovolemia

3. A patient presents with AKI, thrombocytopenia, and microangiopathic hemolytic anemia in the setting of infection. Differentiating secondary (infectious) TMA from primary complement-mediated TMA (aHUS) is challenging. What is the most appropriate initial management when distinction cannot be made rapidly?

A. Start eculizumab immediately in all cases

B. Initiate plasma exchange empirically while awaiting diagnostic results

C. Wait for genetic testing before initiating therapy

D. Treat only with antimicrobials and supportive care

4. Which infection commonly causes a non-oliguric AKI with interstitial nephritis in tropical regions?

A. Dengue

B. Leptospirosis

C. Scrub typhus

D. Chikungunya

5. Which of the following is a common mechanism of AKI following snake envenomation?

A. Minimal change disease

B. Rhabdomyolysis and hemolysis

C. Renal artery stenosis

D. Autoimmune vasculitis

6. Which of the following is the most appropriate indication for choosing peritoneal dialysis over hemodialysis in Tropical AKI?

A. Severe pulmonary edema requiring rapid ultrafiltration

B. Hemodynamically unstable patient without peritonitis

C. Need for rapid potassium removal

D. Severe metabolic acidosis with pH <7.0

7. In patients with capillary leak and hypotension, which of the following is the most appropriate method to assess fluid responsiveness?

A. Central venous pressure (CVP)

B. Serum lactate alone

C. Passive leg raise (PLR) test

D. Urine output alone

8. Which of the following complications is more commonly associated with Sepsis-associated AKI compared with Tropical AKI?

A. Rapid renal recovery

B. Higher mortality and multiorgan failure

C. Less ICU stay

D. Rare progression to CKD

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Comment (2)
Rohit Samant says:

March 20, 2026 at 3:37 pm

Very practical and
Informative

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Dr.pradeep kumar says:

March 20, 2026 at 3:37 pm

Practical based and informative questions🙏

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MCQs – Tropical Acute Kidney Injury (AKI)

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